Because of results seen in flat lab dishes, biologists have believed that cancers cells move through the body in a slow, aimless fashion, resembling an intoxicated person who cannot walk three steps in a straight line. This pattern, called a random walk, may hold true for cells traveling across two-dimensional lab containers, but Johns Hopkins researchers have discovered that for cells moving through three-dimensional spaces within the body, the “drunken” model doesn’t hold true.
Recent news from The Johns Hopkins University
This section contains regularly updated highlights of the news from around The Johns Hopkins University. Links to the complete news reports from the nine schools, the Applied Physics Laboratory and other centers and institutes are to the left, as are links to help news media contact the Johns Hopkins communications offices.
A Johns Hopkins engineer who is designing cancer-fighting nano-size structures that could assemble themselves and deliver treatment to diseased tissue has received a Faculty Early Career Development (CAREER) Award from the National Science Foundation. Honggang Cui, an assistant professor in the Department of Chemical and Biomolecular Engineering at Johns Hopkins, has been given this honor, which is accompanied by nearly $500,000 that will be disbursed over five years.
In life, we sort soiled laundry from clean; ripe fruit from rotten. Two Johns Hopkins engineers say they have found an easy way to use gravity or simple forces to similarly sort microscopic particles and bits of biological matter—including circulating tumor cells.
Johns Hopkins researchers have devised a protein “switch” that instructs cancer cells to produce their own anti-cancer medication. In lab tests, the researchers showed that these switches, working from inside the cells, can activate a powerful cell-killing drug when the device detects a marker linked to cancer. The goal, the scientists said, is to deploy a new type of weapon that causes cancer cells to self-destruct while sparing healthy tissue.
A Johns Hopkins undergraduate team that assembled fragments of DNA in a way that allows cells to respond to electrical “messages” has received recognition in an international contest in the emerging field of synthetic biology. The students competed this month in the latest International Genetically Engineered Machine competition, also known as iGEM 2010.