Among the numerous new tactics that aim to spotlight the so-called cancer driver genes, which produce the most accurate results? To help solve this puzzle, a team of Johns Hopkins computational scientists and cancer experts have devised their own bioinformatics software to evaluate how well the current strategies identify cancer-promoting mutations and distinguish them from benign mutations in cancer cells.
Recent news from The Johns Hopkins University
This section contains regularly updated highlights of the news from around The Johns Hopkins University. Links to the complete news reports from the nine schools, the Applied Physics Laboratory and other centers and institutes are to the left, as are links to help news media contact the Johns Hopkins communications offices.
When a battlefield explosion injures a soldier’s face or neck, the critical air passage between the head and lungs often becomes blocked, which can lead to brain damage and death within minutes. To help treat such injuries, a Johns Hopkins undergraduate team has designed a low-cost, low-tech device dubbed CricSpike that may boost the success rate when combat medics need to create an artificial airway and pump air into the lungs.
It’s tough to play video games when you have no fingers to push buttons on the controller. Just ask Gyorgy (George) Levay, an avid gamer who lost both hands to a meningitis infection five years ago. But Levay and two fellow Johns Hopkins grad students have devised a clever way get him, and others with similar disabilities, back in the game.
Johns Hopkins University graduate programs in nursing, education, medicine, and biomedical engineering remain among the best in the nation, according to the newest U.S. News & World Report rankings of “Best Graduate Schools.”
Five Johns Hopkins graduate students, recently named to the 2016 class of Siebel Scholars, are each pursuing bioengineering projects that could lead to important new diagnostic and treatment advances in healthcare. The merit-based Siebel program has recognized their research skills, academic achievements and leadership qualities by providing $35,000 to each of the five PhD candidates for use in his or her final year of graduate studies.
The Johns Hopkins University and DuPont have signed license and collaboration agreements allowing DuPont to commercialize a garment with innovative features from Johns Hopkins to help protect people on the front lines of the Ebola crisis and future deadly infectious disease outbreaks. DuPont intends to have the first of these garments available in the marketplace during the first half of 2016.
The Johns Hopkins University’s new personal protective suit for front-line health care workers in Ebola outbreaks has been honored as one of 10 finalists in the Social Good category of Fast Company’s 2015 Innovation by Design Awards.
Johns Hopkins Engineering for Professionals, the division of the Johns Hopkins University Whiting School of Engineering that administers part-time and online graduate programs, has announced that students can now complete its Applied Biomedical Engineering program online.
Parkinson’s disease patients whose symptoms such as tremor, muscle stiffness and slowed movement make it tough to hold an eating utensil steady have few options for relief outside of a hospital or clinic. To give these patients another in-home treatment option, Johns Hopkins graduate students have invented a headband-shaped device to deliver noninvasive brain stimulation to help tamp down the symptoms.
To address a global health challenge, a team of Johns Hopkins University biomedical engineering undergraduates has developed a teaching set called the Contraceptive Implant Training Tool Kit or CITT Kit, for short. The medical simulator includes two training models: a stand-alone replica arm and a layered band that can be worn by health workers who act as “patients” during practice sessions.
J. Tilak Ratnanather, a Johns Hopkins expert in brain mapping, and a champion of people with hearing loss, is a recipient of the Presidential Award of Excellence in Science, Mathematics and Engineering Mentoring.
Sandya Subramanian, a Johns Hopkins University senior from Grand Rapids, Mich., has won a scholarship from the Winston Churchill Foundation of the United States for graduate study at England’s University of Cambridge
An advanced protective suit for health care workers who treat Ebola patients, devised by a Johns Hopkins team, is one of the first five awardees in a federal funding contest aimed at quickly devising new tools to combat the deadly disease. The Johns Hopkins prototype is designed to do a better job than current garments in keeping health care workers from coming in contact with Ebola patients’ contagious body fluids, both during treatment and while removing a soiled suit.
Johns Hopkins biomedical engineers have developed a free, browser-based online tool that could speed up the creation of new drugs to treat or prevent Ebola virus infections. The software, called MuPIT Ebola Edition, enables a researcher to visualize Ebola gene mutations in the context of three-dimensional protein structures. It also offers views of antibody binding sites called epitopes that are situated on protein surfaces. These sites may give researchers new targets for preventive vaccines and serums to treat those who are already infected.
Five Johns Hopkins graduate students, recently named to the 2015 class of Siebel Scholars, are each pursuing important research projects in varied bioengineering topics involving promising health-related applications.
Without prompt care, a badly wounded soldier can easily bleed to death while being transported to a distant medical station. Two traditional treatments—tourniquets and medicated gauze pads—often cannot stop the blood loss from a deep wound at the neck, shoulder or groin. To give these soldiers a fighting chance at survival, Johns Hopkins undergraduates have invented an injectable foam system designed to stop profuse bleeding from a wound where a limb or the head is connected to the torso.
Johns Hopkins biomedical engineering students have designed a lightweight, easy-to-conceal shirt-like garment to deliver life-saving shocks to patients experiencing serious heart problems. The students say their design improves upon a wearable defibrillator system that is already in use. Their design changes, the students say, should help persuade patients at risk for sudden cardiac arrest to wear the system around the clock.
When an MRI scan uncovers an unusual architecture or shape in a child’s brain, it’s cause for concern: The malformation may be a sign of disease. But deciding whether that odd-looking anatomy is worrisome or harmless can be difficult. To help doctors reach the right decision, Johns Hopkins researchers are building a detailed digital library of MRI scans collected from children with normal and abnormal brains. The goal, the researchers say, is to give physicians a Google-like search system that will enhance the way they diagnose and treat young patients with brain disorders.
Johns Hopkins Students Win Inventors Contest’s Top Prizes for Heart Treatment Device and Cancer Test
A Johns Hopkins undergraduate biomedical engineering student team that devised a two-part system to improve the way life-saving shocks are delivered to hearts earned first-prize in the undergraduate division of a national Collegiate Inventors Competition. In the graduate-level competition, Isaac Kinde, a Johns Hopkins medical student, received third-place honors for developing a test to detect ovarian and endometrial cancers as part of a team at the Johns Hopkins Kimmel Cancer Center.
Two Johns Hopkins faculty members–Natalia Trayanova and Hans Tomas Bjornsson–have been chosen to receive prestigious National Institutes of Health grants allocated for biomedical research projects that face significant challenges but could lead to major health care payoffs. The Johns Hopkins researchers are among 78 grant recipients nationwide announced Sept. 30 under the High Risk-High Reward Program supported by the National Institutes of Health Common Fund.
Five Johns Hopkins graduate students, recently named to the 2014 class of Siebel Scholars, are pushing the boundaries of medical technology to develop new and improved ways to diagnose and treat cancer, heart disease and other serious health problems. The students are trying to turn stem cells into healthy blood vessels, are testing biological reactions within microscopic droplets and are using advanced imaging techniques to detect disease at an early, treatable stage.
In recognition of their research skills, academic achievements and leadership qualities, the five PhD candidates are being honored as Johns Hopkins’ 2014 Siebel Scholars. The merit-based Siebel program provides $35,000 to each student for use in his or her final year of graduate studies.
When a beating heart slips into an irregular, life-threatening rhythm, the treatment is well known: deliver a burst of electric current from a pacemaker or defibrillator. But because the electricity itself can cause pain, tissue damage and other serious side-effects, a Johns Hopkins-led research team wants to replace these jolts with a kinder, gentler remedy: light. In a paper published Aug. 28 in the online journal Nature Communications, five biomedical engineers from Johns Hopkins and Stony Brook universities described their plan to use biological lab data and an intricate computer model to devise a better way to heal ailing hearts.
Johns Hopkins Receives Grant From Medtronic for Student Engineering Program Focused on Medical Devices for Developing Countries
Medtronic, one of the world’s largest medical technology companies, has entered into an innovative partnership with The Johns Hopkins University, agreeing to provide $200,000 a year for up to three years and skilled mentoring to help biomedical engineering students design new healthcare solutions for underserved patients in developing countries.
When a breast tumor is detected, many women opt to have a lumpectomy, which is surgery designed to remove the diseased tissue while preserving the breast. But during this procedure, doctors cannot learn right away whether all of the cancerous tissue has been removed, with no microscopic signs that cancer cells were left behind. Because of this delay, one in five of these women—up to 66,000 patients annually in the U.S. alone—must return for a second surgery to remove remaining cancer. These follow-up operations boost healthcare costs and can lead to delays in receiving other treatments such as radiation and chemotherapy. To reduce the need for these second surgeries, four Johns Hopkins graduate students have designed a device to allow pathologists to quickly inspect excised breast tissue within 20 minutes, while the patient is still in the operating room.